Combined genetic and epigenetic alterations of the TERT promoter affect clinical and biological behavior of bladder cancer

In urothelial bladder cancer (UBC), risk stratification remains an important unmet need. Limitless self‐renewal, governed by TERT expression and telomerase activation, is crucial for cancer progression. Thus, telomerase activation through the interplay of mutations (TERTp(Mut)) and epigenetic altera...

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Detaylı Bibliyografya
Yayımlandı:Int J Cancer
Asıl Yazarlar: Leão, Ricardo, Lee, Donghyun, Figueiredo, Arnaldo, Hermanns, Thomas, Wild, Peter, Komosa, Martin, Lau, Irene, Mistry, Mathew, Nunes, Nuno Miguel, Price, Aryeh J., Zhang, Cindy, Lipman, Tatiana, Poyet, Cédric, Valtcheva, Nadejda, Oehl, Kathrin, Coelho, Hugo, Sayyid, Rashid, Gomes, Ana Melo, Prado e Castro, Ligia, Sweet, Joan, Vinagre, João, Apolónio, Joana, Stephens, Derek, Faleiro, Inês, Fadaak, Kamel, Richard, Patrick O., Kulkarni, Girish, Zlotta, Alexandre R., Hamilton, Robert J., Castelo‐Branco, Pedro, Tabori, Uri
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley & Sons, Inc. 2018
Konular:
Tumor Markers and Signatures
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519346/
https://ncbi.nlm.nih.gov/pubmed/30350309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31935
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