Combined genetic and epigenetic alterations of the TERT promoter affect clinical and biological behavior of bladder cancer

In urothelial bladder cancer (UBC), risk stratification remains an important unmet need. Limitless self‐renewal, governed by TERT expression and telomerase activation, is crucial for cancer progression. Thus, telomerase activation through the interplay of mutations (TERTp(Mut)) and epigenetic altera...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Int J Cancer
Главные авторы: Leão, Ricardo, Lee, Donghyun, Figueiredo, Arnaldo, Hermanns, Thomas, Wild, Peter, Komosa, Martin, Lau, Irene, Mistry, Mathew, Nunes, Nuno Miguel, Price, Aryeh J., Zhang, Cindy, Lipman, Tatiana, Poyet, Cédric, Valtcheva, Nadejda, Oehl, Kathrin, Coelho, Hugo, Sayyid, Rashid, Gomes, Ana Melo, Prado e Castro, Ligia, Sweet, Joan, Vinagre, João, Apolónio, Joana, Stephens, Derek, Faleiro, Inês, Fadaak, Kamel, Richard, Patrick O., Kulkarni, Girish, Zlotta, Alexandre R., Hamilton, Robert J., Castelo‐Branco, Pedro, Tabori, Uri
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley & Sons, Inc. 2018
Предметы:
Tumor Markers and Signatures
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519346/
https://ncbi.nlm.nih.gov/pubmed/30350309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.31935
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы