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Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer
BACKGROUND: Limitless self-renewal is one of the hallmarks of cancer and is attained by telomere maintenance, essentially through telomerase (hTERT) activation. Transcriptional regulation of hTERT is believed to play a major role in telomerase activation in human cancers. MAIN BODY: The dominant int...
Enregistré dans:
| Publié dans: | J Biomed Sci |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846307/ https://ncbi.nlm.nih.gov/pubmed/29526163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-018-0422-8 |
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