A cancer specific hypermethylation signature of the TERT promoter predicts biochemical relapse in prostate cancer: a retrospective cohort study

The identification of new biomarkers to differentiate between indolent and aggressive prostate tumors is an important unmet need. We examined the role of THOR (TERT Hypermethylated Oncological Region) as a diagnostic and prognostic biomarker in prostate cancer (PCa). We analyzed THOR in common cance...

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Udgivet i:Oncotarget
Main Authors: Castelo-Branco, Pedro, Leão, Ricardo, Lipman, Tatiana, Campbell, Brittany, Lee, Donghyun, Price, Aryeh, Zhang, Cindy, Heidari, Abolfazl, Stephens, Derek, Boerno, Stefan, Coelho, Hugo, Gomes, Ana, Domingos, Celia, Apolonio, Joana D., Schäfer, Georg, Bristow, Robert G., Schweiger, Michal R., Hamilton, Robert, Zlotta, Alexandre, Figueiredo, Arnaldo, Klocker, Helmut, Sültmann, Holger, Tabori, Uri
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295385/
https://ncbi.nlm.nih.gov/pubmed/27437772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10639
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