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Extent of constitutive histone H2AX phosphorylation on Ser‐139 varies in cells with different TP53 status
Abstract. In response to DNA damage by genotoxic agents, histone H2AX is phosphorylated on Ser‐139. However, during the cell cycle, predominantly in S and G(2)M phase, histone H2AX is also phosphorylated in untreated normal and tumour cells. This constitutive H2AX phosphorylation is markedly reduce...
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| 出版年: | Cell Prolif |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Publishing Ltd
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6496136/ https://ncbi.nlm.nih.gov/pubmed/16872365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2006.00387.x |
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