Cytometry of ATM Activation and Histone H2AX Phosphorylation to Estimate Extent of DNA Damage Induced by Exogenous Agents

This review covers the topic of cytometric assessment of activation of Ataxia telangiectasia mutated (ATM) protein kinase and histone H2AX phosphorylation on Ser139 in response to DNA damage, particularly the damage that involves formation of DNA double-strand breaks. Briefly described are molecular...

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Main Authors: Tanaka, Toshiki, Huang, Xuan, Halicka, H. Dorota, Zhao, Hong, Traganos, Frank, Albino, Anthony P., Dai, Wei, Darzynkiewicz, Zbigniew
格式: Artigo
語言:Inglês
出版: 2007
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855668/
https://ncbi.nlm.nih.gov/pubmed/17622968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.20426
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