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Cytometry of ATM Activation and Histone H2AX Phosphorylation to Estimate Extent of DNA Damage Induced by Exogenous Agents

This review covers the topic of cytometric assessment of activation of Ataxia telangiectasia mutated (ATM) protein kinase and histone H2AX phosphorylation on Ser139 in response to DNA damage, particularly the damage that involves formation of DNA double-strand breaks. Briefly described are molecular...

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Detalhes bibliográficos
Main Authors: Tanaka, Toshiki, Huang, Xuan, Halicka, H. Dorota, Zhao, Hong, Traganos, Frank, Albino, Anthony P., Dai, Wei, Darzynkiewicz, Zbigniew
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855668/
https://ncbi.nlm.nih.gov/pubmed/17622968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.20426
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