Cytometry of ATM Activation and Histone H2AX Phosphorylation to Estimate Extent of DNA Damage Induced by Exogenous Agents

This review covers the topic of cytometric assessment of activation of Ataxia telangiectasia mutated (ATM) protein kinase and histone H2AX phosphorylation on Ser139 in response to DNA damage, particularly the damage that involves formation of DNA double-strand breaks. Briefly described are molecular...

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Bibliographische Detailangaben
Hauptverfasser: Tanaka, Toshiki, Huang, Xuan, Halicka, H. Dorota, Zhao, Hong, Traganos, Frank, Albino, Anthony P., Dai, Wei, Darzynkiewicz, Zbigniew
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855668/
https://ncbi.nlm.nih.gov/pubmed/17622968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cyto.a.20426
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