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Constitutive histone H2AX phosphorylation and ATM activation are strongly amplified during mitogenic stimulation of lymphocytes

Abstract.  Objectives: We recently postulated that constitutive activation of Ataxia Telangiectasia, Mutated (CAA) and constitutive histone H2AX phosphorylation (CHP) seen in cells not treated with genotoxic agents are the events triggered by DNA damage caused by endogenous reactive oxygen species (...

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מידע ביבליוגרפי
Main Authors: Tanaka, T., Kajstura, M., Halicka, H. D., Traganos, F., Darzynkiewicz, Z.
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Publishing Ltd 2007
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3860878/
https://ncbi.nlm.nih.gov/pubmed/17227291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2007.00417.x
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