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Extent of constitutive histone H2AX phosphorylation on Ser‐139 varies in cells with different TP53 status
Abstract. In response to DNA damage by genotoxic agents, histone H2AX is phosphorylated on Ser‐139. However, during the cell cycle, predominantly in S and G(2)M phase, histone H2AX is also phosphorylated in untreated normal and tumour cells. This constitutive H2AX phosphorylation is markedly reduce...
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| Опубликовано в: : | Cell Prolif |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Publishing Ltd
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6496136/ https://ncbi.nlm.nih.gov/pubmed/16872365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2006.00387.x |
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