Synchronization in the cell cycle by inhibitors of DNA replication induces histone H2AX phosphorylation: an indication of DNA damage

Abstract.   Several methods to synchronize cultured cells in the cell cycle are based on temporary inhibition of DNA replication. Previously it has been reported that cells synchronized this way exhibited significant growth imbalance and unscheduled expression of cyclins A and B1. We have now observ...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Kurose, A., Tanaka, T., Huang, X., Traganos, F., Darzynkiewicz, Z.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6496703/
https://ncbi.nlm.nih.gov/pubmed/16672000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2006.00380.x
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