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ATM activation and histone H2AX phosphorylation as indicators of DNA damage by DNA topoisomerase I inhibitor topotecan and during apoptosis
Abstract. Damage that engenders DNA double‐strand breaks (DSBs) activates ataxia telangiectasia mutated (ATM) kinase through its auto‐ or trans‐phosphorylation on Ser1981 and activated ATM is one of the mediators of histone H2AX phosphorylation on Ser139. The present study was designed to explore:...
में बचाया:
| में प्रकाशित: | Cell Prolif |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Blackwell Science Ltd
2006
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6496121/ https://ncbi.nlm.nih.gov/pubmed/16426422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2184.2006.00364.x |
| टैग : |
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