Structural mechanism underlying G protein family-specific regulation of G protein-gated inwardly rectifying potassium channel

G protein-gated inwardly rectifying potassium channel (GIRK) plays a key role in regulating neurotransmission. GIRK is opened by the direct binding of the G protein βγ subunit (Gβγ), which is released from the heterotrimeric G protein (Gαβγ) upon the activation of G protein-coupled receptors (GPCRs)...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Nat Commun
Hlavní autoři: Kano, Hanaho, Toyama, Yuki, Imai, Shunsuke, Iwahashi, Yuta, Mase, Yoko, Yokogawa, Mariko, Osawa, Masanori, Shimada, Ichio
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6494913/
https://ncbi.nlm.nih.gov/pubmed/31043612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10038-x
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky