Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation

Idiopathic pulmonary fibrosis (IPF) is a deadly disease with a poor prognosis and few treatment options. Pathological remodeling of the extracellular matrix (ECM) is a key factor that drives the disease pathogenesis, although the underlying mechanisms remain unknown. Alternative polyadenylation (APA...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Weng, Tingting, Ko, Junsuk, Masamha, Chioniso P., Xia, Zheng, Xiang, Yu, Chen, Ning-yuan, Molina, Jose G., Collum, Scott, Mertens, Tinne C., Luo, Fayong, Philip, Kemly, Davies, Jonathan, Huang, Jingjing, Wilson, Cory, Thandavarayan, Rajarajan A., Bruckner, Brian A., Jyothula, Soma S.K., Volcik, Kelly A., Li, Lei, Han, Leng, Li, Wei, Assassi, Shervin, Karmouty-Quintana, Harry, Wagner, Eric J., Blackburn, Michael R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486348/
https://ncbi.nlm.nih.gov/pubmed/30830875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122106
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