Adenosine and hyaluronan promote lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema

Combined pulmonary fibrosis and emphysema (CPFE) is a syndrome that predominantly affects male smokers or ex-smokers and it has a mortality rate of 55% and a median survival of 5 years. Pulmonary hypertension (PH) is a frequently fatal complication of CPFE. Despite this dismal prognosis, no curative...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Collum, Scott D., Molina, Jose G., Hanmandlu, Ankit, Bi, Weizhen, Pedroza, Mesias, Mertens, Tinne C. J., Wareing, Nancy, Wei, Wang, Wilson, Cory, Sun, Wenchao, Rajadas, Jayakumar, Bollyky, Paul L., Philip, Kemly M., Ren, Dewei, Thandavarayan, Rajarajan A., Bruckner, Brian A., Xia, Yang, Blackburn, Michael R., Karmouty-Quintana, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550050/
https://ncbi.nlm.nih.gov/pubmed/31036697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.038711
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