Adenosine and hyaluronan promote lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema

Combined pulmonary fibrosis and emphysema (CPFE) is a syndrome that predominantly affects male smokers or ex-smokers and it has a mortality rate of 55% and a median survival of 5 years. Pulmonary hypertension (PH) is a frequently fatal complication of CPFE. Despite this dismal prognosis, no curative...

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Опубликовано в: :Dis Model Mech
Главные авторы: Collum, Scott D., Molina, Jose G., Hanmandlu, Ankit, Bi, Weizhen, Pedroza, Mesias, Mertens, Tinne C. J., Wareing, Nancy, Wei, Wang, Wilson, Cory, Sun, Wenchao, Rajadas, Jayakumar, Bollyky, Paul L., Philip, Kemly M., Ren, Dewei, Thandavarayan, Rajarajan A., Bruckner, Brian A., Xia, Yang, Blackburn, Michael R., Karmouty-Quintana, Harry
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists Ltd 2019
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550050/
https://ncbi.nlm.nih.gov/pubmed/31036697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.038711
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