Adenosine and hyaluronan promote lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema

Combined pulmonary fibrosis and emphysema (CPFE) is a syndrome that predominantly affects male smokers or ex-smokers and it has a mortality rate of 55% and a median survival of 5 years. Pulmonary hypertension (PH) is a frequently fatal complication of CPFE. Despite this dismal prognosis, no curative...

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Udgivet i:Dis Model Mech
Main Authors: Collum, Scott D., Molina, Jose G., Hanmandlu, Ankit, Bi, Weizhen, Pedroza, Mesias, Mertens, Tinne C. J., Wareing, Nancy, Wei, Wang, Wilson, Cory, Sun, Wenchao, Rajadas, Jayakumar, Bollyky, Paul L., Philip, Kemly M., Ren, Dewei, Thandavarayan, Rajarajan A., Bruckner, Brian A., Xia, Yang, Blackburn, Michael R., Karmouty-Quintana, Harry
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550050/
https://ncbi.nlm.nih.gov/pubmed/31036697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.038711
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