Adenosine and hyaluronan promote lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema

Combined pulmonary fibrosis and emphysema (CPFE) is a syndrome that predominantly affects male smokers or ex-smokers and it has a mortality rate of 55% and a median survival of 5 years. Pulmonary hypertension (PH) is a frequently fatal complication of CPFE. Despite this dismal prognosis, no curative...

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Detaylı Bibliyografya
Yayımlandı:Dis Model Mech
Asıl Yazarlar: Collum, Scott D., Molina, Jose G., Hanmandlu, Ankit, Bi, Weizhen, Pedroza, Mesias, Mertens, Tinne C. J., Wareing, Nancy, Wei, Wang, Wilson, Cory, Sun, Wenchao, Rajadas, Jayakumar, Bollyky, Paul L., Philip, Kemly M., Ren, Dewei, Thandavarayan, Rajarajan A., Bruckner, Brian A., Xia, Yang, Blackburn, Michael R., Karmouty-Quintana, Harry
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists Ltd 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550050/
https://ncbi.nlm.nih.gov/pubmed/31036697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.038711
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