Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation

Idiopathic pulmonary fibrosis (IPF) is a deadly disease with a poor prognosis and few treatment options. Pathological remodeling of the extracellular matrix (ECM) is a key factor that drives the disease pathogenesis, although the underlying mechanisms remain unknown. Alternative polyadenylation (APA...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Weng, Tingting, Ko, Junsuk, Masamha, Chioniso P., Xia, Zheng, Xiang, Yu, Chen, Ning-yuan, Molina, Jose G., Collum, Scott, Mertens, Tinne C., Luo, Fayong, Philip, Kemly, Davies, Jonathan, Huang, Jingjing, Wilson, Cory, Thandavarayan, Rajarajan A., Bruckner, Brian A., Jyothula, Soma S.K., Volcik, Kelly A., Li, Lei, Han, Leng, Li, Wei, Assassi, Shervin, Karmouty-Quintana, Harry, Wagner, Eric J., Blackburn, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486348/
https://ncbi.nlm.nih.gov/pubmed/30830875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122106
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