Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation

Idiopathic pulmonary fibrosis (IPF) is a deadly disease with a poor prognosis and few treatment options. Pathological remodeling of the extracellular matrix (ECM) is a key factor that drives the disease pathogenesis, although the underlying mechanisms remain unknown. Alternative polyadenylation (APA...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Weng, Tingting, Ko, Junsuk, Masamha, Chioniso P., Xia, Zheng, Xiang, Yu, Chen, Ning-yuan, Molina, Jose G., Collum, Scott, Mertens, Tinne C., Luo, Fayong, Philip, Kemly, Davies, Jonathan, Huang, Jingjing, Wilson, Cory, Thandavarayan, Rajarajan A., Bruckner, Brian A., Jyothula, Soma S.K., Volcik, Kelly A., Li, Lei, Han, Leng, Li, Wei, Assassi, Shervin, Karmouty-Quintana, Harry, Wagner, Eric J., Blackburn, Michael R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2019
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486348/
https://ncbi.nlm.nih.gov/pubmed/30830875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122106
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