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Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation

Idiopathic pulmonary fibrosis (IPF) is a deadly disease with a poor prognosis and few treatment options. Pathological remodeling of the extracellular matrix (ECM) is a key factor that drives the disease pathogenesis, although the underlying mechanisms remain unknown. Alternative polyadenylation (APA...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Clin Invest
Main Authors: Weng, Tingting, Ko, Junsuk, Masamha, Chioniso P., Xia, Zheng, Xiang, Yu, Chen, Ning-yuan, Molina, Jose G., Collum, Scott, Mertens, Tinne C., Luo, Fayong, Philip, Kemly, Davies, Jonathan, Huang, Jingjing, Wilson, Cory, Thandavarayan, Rajarajan A., Bruckner, Brian A., Jyothula, Soma S.K., Volcik, Kelly A., Li, Lei, Han, Leng, Li, Wei, Assassi, Shervin, Karmouty-Quintana, Harry, Wagner, Eric J., Blackburn, Michael R.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486348/
https://ncbi.nlm.nih.gov/pubmed/30830875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122106
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