Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation

Idiopathic pulmonary fibrosis (IPF) is a deadly disease with a poor prognosis and few treatment options. Pathological remodeling of the extracellular matrix (ECM) is a key factor that drives the disease pathogenesis, although the underlying mechanisms remain unknown. Alternative polyadenylation (APA...

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Udgivet i:J Clin Invest
Main Authors: Weng, Tingting, Ko, Junsuk, Masamha, Chioniso P., Xia, Zheng, Xiang, Yu, Chen, Ning-yuan, Molina, Jose G., Collum, Scott, Mertens, Tinne C., Luo, Fayong, Philip, Kemly, Davies, Jonathan, Huang, Jingjing, Wilson, Cory, Thandavarayan, Rajarajan A., Bruckner, Brian A., Jyothula, Soma S.K., Volcik, Kelly A., Li, Lei, Han, Leng, Li, Wei, Assassi, Shervin, Karmouty-Quintana, Harry, Wagner, Eric J., Blackburn, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6486348/
https://ncbi.nlm.nih.gov/pubmed/30830875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122106
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