Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis

BACKGROUND AND PURPOSE: Group III pulmonary hypertension (PH) is a highly lethal and widespread lung disorder that is a common complication in idiopathic pulmonary fibrosis (IPF) where it is considered to be the single most significant predictor of mortality. While increased levels of hyaluronan hav...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Collum, Scott D, Chen, Ning‐Yuan, Hernandez, Adriana M, Hanmandlu, Ankit, Sweeney, Heather, Mertens, Tinne C J, Weng, Tingting, Luo, Fayong, Molina, Jose G, Davies, Jonathan, Horan, Ian P, Morrell, Nick W, Amione‐Guerra, Javier, Al‐Jabbari, Odeaa, Youker, Keith, Sun, Wenchao, Rajadas, Jayakumar, Bollyky, Paul L, Akkanti, Bindu H, Jyothula, Soma, Sinha, Neeraj, Guha, Ashrith, Karmouty‐Quintana, Harry
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5595757/
https://ncbi.nlm.nih.gov/pubmed/28688167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13947
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