Chimeric Hemagglutinin-Based Influenza Virus Vaccines Induce Protective Stalk-Specific Humoral Immunity and Cellular Responses in Mice

The high variation of the influenza virus hemagglutinin (HA), particularly of its immunodominant head epitopes, makes it necessary to reformulate seasonal influenza virus vaccines every year. Novel influenza virus vaccines that redirect the immune response toward conserved epitopes of the HA stalk d...

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Publicat a:Immunohorizons
Autors principals: Choi, Angela, Bouzya, Badiaa, Cortés Franco, Klaus-Daniel, Stadlbauer, Daniel, Rajabhathor, Arvind, Rouxel, Ronan N., Mainil, Roland, Van der Wielen, Marie, Palese, Peter, García-Sastre, Adolfo, Innis, Bruce L., Krammer, Florian, Schotsaert, Michael, Mallett, Corey P., Nachbagauer, Raffael
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485968/
https://ncbi.nlm.nih.gov/pubmed/31032479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.1900022
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