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Age Dependence and Isotype Specificity of Influenza Virus Hemagglutinin Stalk-Reactive Antibodies in Humans

Influenza remains a major global health burden. Seasonal vaccines offer protection but can be rendered less effective when the virus undergoes extensive antigenic drift. Antibodies that target the highly conserved hemagglutinin stalk can protect against drifted viruses, and vaccine constructs design...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Nachbagauer, Raffael, Choi, Angela, Izikson, Ruvim, Cox, Manon M., Palese, Peter, Krammer, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725014/
https://ncbi.nlm.nih.gov/pubmed/26787832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01996-15
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