Age Dependence and Isotype Specificity of Influenza Virus Hemagglutinin Stalk-Reactive Antibodies in Humans

Influenza remains a major global health burden. Seasonal vaccines offer protection but can be rendered less effective when the virus undergoes extensive antigenic drift. Antibodies that target the highly conserved hemagglutinin stalk can protect against drifted viruses, and vaccine constructs design...

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Veröffentlicht in:mBio
Hauptverfasser: Nachbagauer, Raffael, Choi, Angela, Izikson, Ruvim, Cox, Manon M., Palese, Peter, Krammer, Florian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Microbiology 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725014/
https://ncbi.nlm.nih.gov/pubmed/26787832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01996-15
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