A chimeric haemagglutinin-based influenza split virion vaccine adjuvanted with AS03 induces protective stalk-reactive antibodies in mice

Seasonal influenza virus vaccines are generally effective at preventing disease, but need to be well matched to circulating virus strains for maximum benefit. Influenza viruses constantly undergo antigenic changes because of their high mutation rate in the immunodominant haemagglutinin (HA) head dom...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:NPJ Vaccines
Päätekijät: Nachbagauer, Raffael, Kinzler, David, Choi, Angela, Hirsh, Ariana, Beaulieu, Edith, Lecrenier, Nicolas, Innis, Bruce L, Palese, Peter, Mallett, Corey P, Krammer, Florian
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2016
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5707880/
https://ncbi.nlm.nih.gov/pubmed/29250436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npjvaccines.2016.15
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia