Chimeric Hemagglutinin-Based Influenza Virus Vaccines Induce Protective Stalk-Specific Humoral Immunity and Cellular Responses in Mice

The high variation of the influenza virus hemagglutinin (HA), particularly of its immunodominant head epitopes, makes it necessary to reformulate seasonal influenza virus vaccines every year. Novel influenza virus vaccines that redirect the immune response toward conserved epitopes of the HA stalk d...

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Detalhes bibliográficos
Publicado no:Immunohorizons
Main Authors: Choi, Angela, Bouzya, Badiaa, Cortés Franco, Klaus-Daniel, Stadlbauer, Daniel, Rajabhathor, Arvind, Rouxel, Ronan N., Mainil, Roland, Van der Wielen, Marie, Palese, Peter, García-Sastre, Adolfo, Innis, Bruce L., Krammer, Florian, Schotsaert, Michael, Mallett, Corey P., Nachbagauer, Raffael
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485968/
https://ncbi.nlm.nih.gov/pubmed/31032479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/immunohorizons.1900022
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