Hemagglutinin Stalk Immunity Reduces Influenza Virus Replication and Transmission in Ferrets

We assessed whether influenza virus hemagglutinin stalk-based immunity protects ferrets against aerosol-transmitted H1N1 influenza virus infection. Immunization of ferrets by a universal influenza virus vaccine strategy based on viral vectors expressing chimeric hemagglutinin constructs induced stal...

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Publicado en:J Virol
Autores principales: Nachbagauer, Raffael, Miller, Matthew S., Hai, Rong, Ryder, Alex B., Rose, John K., Palese, Peter, García-Sastre, Adolfo, Krammer, Florian, Albrecht, Randy A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810634/
https://ncbi.nlm.nih.gov/pubmed/26719251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02481-15
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