Induction of Broadly Reactive Anti-Hemagglutinin Stalk Antibodies by an H5N1 Vaccine in Humans

Influenza virus infections are a major public health concern and cause significant morbidity and mortality worldwide. Current vaccines are effective but strain specific due to their focus on the immunodominant globular head domain of the hemagglutinin (HA). It has been hypothesized that sequential e...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Nachbagauer, Raffael, Wohlbold, Teddy John, Hirsh, Ariana, Hai, Rong, Sjursen, Haakon, Palese, Peter, Cox, Rebecca J., Krammer, Florian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249097/
https://ncbi.nlm.nih.gov/pubmed/25210189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02133-14
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