Induction of Broadly Reactive Anti-Hemagglutinin Stalk Antibodies by an H5N1 Vaccine in Humans

Influenza virus infections are a major public health concern and cause significant morbidity and mortality worldwide. Current vaccines are effective but strain specific due to their focus on the immunodominant globular head domain of the hemagglutinin (HA). It has been hypothesized that sequential e...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Nachbagauer, Raffael, Wohlbold, Teddy John, Hirsh, Ariana, Hai, Rong, Sjursen, Haakon, Palese, Peter, Cox, Rebecca J., Krammer, Florian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249097/
https://ncbi.nlm.nih.gov/pubmed/25210189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02133-14
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