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Induction of Broadly Reactive Anti-Hemagglutinin Stalk Antibodies by an H5N1 Vaccine in Humans

Influenza virus infections are a major public health concern and cause significant morbidity and mortality worldwide. Current vaccines are effective but strain specific due to their focus on the immunodominant globular head domain of the hemagglutinin (HA). It has been hypothesized that sequential e...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Nachbagauer, Raffael, Wohlbold, Teddy John, Hirsh, Ariana, Hai, Rong, Sjursen, Haakon, Palese, Peter, Cox, Rebecca J., Krammer, Florian
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249097/
https://ncbi.nlm.nih.gov/pubmed/25210189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02133-14
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