Pandemic influenza virus vaccines boost hemagglutinin stalk-specific antibody responses in primed adult and pediatric cohorts

Licensed influenza virus vaccines target the head domain of the hemagglutinin (HA) glycoprotein which undergoes constant antigenic drift. The highly conserved HA stalk domain is an attractive target to increase immunologic breadth required for universal influenza virus vaccines. We tested the hypoth...

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Bibliographic Details
Published in:NPJ Vaccines
Main Authors: Nachbagauer, Raffael, Salaun, Bruno, Stadlbauer, Daniel, Behzadi, Mohammad A., Friel, Damien, Rajabhathor, Arvind, Choi, Angela, Albrecht, Randy A., Debois, Muriel, García-Sastre, Adolfo, Rouxel, Ronan N., Sun, Weina, Palese, Peter, Mallett, Corey P., Innis, Bruce L., Krammer, Florian, Claeys, Carine
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6898674/
https://ncbi.nlm.nih.gov/pubmed/31839997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41541-019-0147-z
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