Activity of human serum antibodies in a hemagglutinin stalk-based ADCC reporter assay correlates with activity in a CD107a degranulation assay

The stalk of the influenza virus hemagglutinin (HA) is an attractive target for antibody-based universal influenza virus vaccine development. While antibodies that target this part of the virus can be neutralizing, it has been shown in recent years that Fc receptor-mediated effector functions are of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Vaccine
Hauptverfasser: Chromikova, Veronika, Tan, Jessica, Aslam, Sadaf, Rajabhathor, Arvind, Bermudez-Gonzalez, Maria, Ayllon, Juan, Simon, Viviana, García-Sastre, Adolfo, Salaun, Bruno, Nachbagauer, Raffael, Krammer, Florian
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117648/
https://ncbi.nlm.nih.gov/pubmed/31959425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2020.01.008
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge