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Reverse GWAS: Using genetics to identify and model phenotypic subtypes

Recent and classical work has revealed biologically and medically significant subtypes in complex diseases and traits. However, relevant subtypes are often unknown, unmeasured, or actively debated, making automated statistical approaches to subtype definition valuable. We propose reverse GWAS (RGWAS...

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Bibliografische gegevens
Gepubliceerd in:PLoS Genet
Hoofdauteurs: Dahl, Andy, Cai, Na, Ko, Arthur, Laakso, Markku, Pajukanta, Päivi, Flint, Jonathan, Zaitlen, Noah
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469799/
https://ncbi.nlm.nih.gov/pubmed/30951530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008009
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