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Reverse GWAS: Using genetics to identify and model phenotypic subtypes

Recent and classical work has revealed biologically and medically significant subtypes in complex diseases and traits. However, relevant subtypes are often unknown, unmeasured, or actively debated, making automated statistical approaches to subtype definition valuable. We propose reverse GWAS (RGWAS...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Dahl, Andy, Cai, Na, Ko, Arthur, Laakso, Markku, Pajukanta, Päivi, Flint, Jonathan, Zaitlen, Noah
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469799/
https://ncbi.nlm.nih.gov/pubmed/30951530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008009
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