Phenotype-Specific Enrichment of Mendelian Disorder Genes near GWAS Regions across 62 Complex Traits

Although recent studies provide evidence for a common genetic basis between complex traits and Mendelian disorders, a thorough quantification of their overlap in a phenotype-specific manner remains elusive. Here, we have quantified the overlap of genes identified through large-scale genome-wide asso...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Hum Genet
Egile Nagusiak: Freund, Malika Kumar, Burch, Kathryn S., Shi, Huwenbo, Mancuso, Nicholas, Kichaev, Gleb, Garske, Kristina M., Pan, David Z., Miao, Zong, Mohlke, Karen L., Laakso, Markku, Pajukanta, Päivi, Pasaniuc, Bogdan, Arboleda, Valerie A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174356/
https://ncbi.nlm.nih.gov/pubmed/30290150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2018.08.017
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