Wird geladen...
Leveraging Polygenic Functional Enrichment to Improve GWAS Power
Functional genomics data has the potential to increase GWAS power by identifying SNPs that have a higher prior probability of association. Here, we introduce a method that leverages polygenic functional enrichment to incorporate coding, conserved, regulatory, and LD-related genomic annotations into...
Gespeichert in:
| Veröffentlicht in: | Am J Hum Genet |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2019
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6323418/ https://ncbi.nlm.nih.gov/pubmed/30595370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2018.11.008 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|