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Leveraging Functional-Annotation Data in Trans-ethnic Fine-Mapping Studies

Localization of causal variants underlying known risk loci is one of the main research challenges following genome-wide association studies. Risk loci are typically dissected through fine-mapping experiments in trans-ethnic cohorts for leveraging the variability in the local genetic structure across...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: Kichaev, Gleb, Pasaniuc, Bogdan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4573268/
https://ncbi.nlm.nih.gov/pubmed/26189819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.06.007
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