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Mixed model association for biobank-scale data sets

Biobank-based genome-wide association studies are enabling exciting insights in complex trait genetics, but much uncertainty remains over best practices for optimizing statistical power and computational efficiency in GWAS while controlling confounders. Here, we introduce a much faster version of ou...

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Bibliografiska uppgifter
I publikationen:Nat Genet
Huvudupphovsmän: Loh, Po-Ru, Kichaev, Gleb, Gazal, Steven, Schoech, Armin P, Price, Alkes L
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309610/
https://ncbi.nlm.nih.gov/pubmed/29892013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-018-0144-6
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