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Localizing Components of Shared Transethnic Genetic Architecture of Complex Traits from GWAS Summary Data
Despite strong transethnic genetic correlations reported in the literature for many complex traits, the non-transferability of polygenic risk scores across populations suggests the presence of population-specific components of genetic architecture. We propose an approach that models GWAS summary dat...
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| Опубликовано в: : | Am J Hum Genet |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7273527/ https://ncbi.nlm.nih.gov/pubmed/32442408 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2020.04.012 |
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