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Integrating Gene Expression with Summary Association Statistics to Identify Genes Associated with 30 Complex Traits
Although genome-wide association studies (GWASs) have identified thousands of risk loci for many complex traits and diseases, the causal variants and genes at these loci remain largely unknown. Here, we introduce a method for estimating the local genetic correlation between gene expression and a com...
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| Udgivet i: | Am J Hum Genet |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5339290/ https://ncbi.nlm.nih.gov/pubmed/28238358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2017.01.031 |
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