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Local Genetic Correlation Gives Insights into the Shared Genetic Architecture of Complex Traits

Although genetic correlations between complex traits provide valuable insights into epidemiological and etiological studies, a precise quantification of which genomic regions disproportionately contribute to the genome-wide correlation is currently lacking. Here, we introduce ρ-HESS, a technique to...

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Détails bibliographiques
Publié dans:Am J Hum Genet
Auteurs principaux: Shi, Huwenbo, Mancuso, Nicholas, Spendlove, Sarah, Pasaniuc, Bogdan
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5673668/
https://ncbi.nlm.nih.gov/pubmed/29100087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2017.09.022
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