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Accurate estimation of SNP-heritability from biobank-scale data irrespective of genetic architecture
SNP-heritability is a fundamental quantity in the study of complex traits. Recent works have shown that existing methods to estimate genome-wide SNP-heritability yield biases when their assumptions are violated. While various approaches have been proposed to account for frequency- and LD-dependent g...
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| Publié dans: | Nat Genet |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6686906/ https://ncbi.nlm.nih.gov/pubmed/31358995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41588-019-0465-0 |
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