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A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context

Genetic studies of metabolites have identified thousands of variants, many of which are associated with downstream metabolic and obesogenic disorders. However, these studies have relied on univariate analyses, reducing power and limiting context-specific understanding. Here we aim to provide an inte...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Gallois, Apolline, Mefford, Joel, Ko, Arthur, Vaysse, Amaury, Julienne, Hanna, Ala-Korpela, Mika, Laakso, Markku, Zaitlen, Noah, Pajukanta, Päivi, Aschard, Hugues
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803661/
https://ncbi.nlm.nih.gov/pubmed/31636271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12703-7
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