A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context

Genetic studies of metabolites have identified thousands of variants, many of which are associated with downstream metabolic and obesogenic disorders. However, these studies have relied on univariate analyses, reducing power and limiting context-specific understanding. Here we aim to provide an inte...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Gallois, Apolline, Mefford, Joel, Ko, Arthur, Vaysse, Amaury, Julienne, Hanna, Ala-Korpela, Mika, Laakso, Markku, Zaitlen, Noah, Pajukanta, Päivi, Aschard, Hugues
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803661/
https://ncbi.nlm.nih.gov/pubmed/31636271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12703-7
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