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Reverse GWAS: Using genetics to identify and model phenotypic subtypes

Recent and classical work has revealed biologically and medically significant subtypes in complex diseases and traits. However, relevant subtypes are often unknown, unmeasured, or actively debated, making automated statistical approaches to subtype definition valuable. We propose reverse GWAS (RGWAS...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Dahl, Andy, Cai, Na, Ko, Arthur, Laakso, Markku, Pajukanta, Päivi, Flint, Jonathan, Zaitlen, Noah
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469799/
https://ncbi.nlm.nih.gov/pubmed/30951530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008009
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