Reverse GWAS: Using genetics to identify and model phenotypic subtypes

Recent and classical work has revealed biologically and medically significant subtypes in complex diseases and traits. However, relevant subtypes are often unknown, unmeasured, or actively debated, making automated statistical approaches to subtype definition valuable. We propose reverse GWAS (RGWAS...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Genet
Main Authors: Dahl, Andy, Cai, Na, Ko, Arthur, Laakso, Markku, Pajukanta, Päivi, Flint, Jonathan, Zaitlen, Noah
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469799/
https://ncbi.nlm.nih.gov/pubmed/30951530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008009
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