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Oxanosine monophosphate is a covalent inhibitor of inosine 5’-monophosphate dehydrogenase

Reactive nitrogen species (RNS) are produced during infection and inflammation and the effects of these agents on proteins, DNA and lipids are well recognized. In contrast, the effects of RNS damaged metabolites are less appreciated. 5–Amino–3–β–(D–ribofuranosyl)–3 H–imidazo–[4,5–d][1,3]oxazine–7–on...

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Bibliografische gegevens
Gepubliceerd in:Chem Res Toxicol
Hoofdauteurs: Yu, Runhan, Kim, Youngchang, Maltseva, Natalia, Braunstein, Philip, Joachimiak, Andrzej, Hedstrom, Lizbeth
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467267/
https://ncbi.nlm.nih.gov/pubmed/30746940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00342
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