Triazole inhibitors of Cryptosporidium parvum inosine 5′-monophosphate dehydrogenase

Cryptosporidium parvum is an important human pathogen and potential bioterrorism agent. This protozoan parasite cannot salvage guanine or guanosine and therefore relies on inosine 5′-monophosphate dehydrogenase (IMPDH) for biosynthesis of guanine nucleotides and hence for survival. Since C. parvum I...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Maurya, Sushil K., Gollapalli, Deviprasad R., Kirubakaran, Sivapriya, Zhang, Minjia, Johnson, Corey R., Benjamin, Nicole N., Hedstrom, Lizbeth, Cuny, Gregory D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810100/
https://ncbi.nlm.nih.gov/pubmed/19624136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900410u
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg