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Selective and potent urea inhibitors of Cryptosporidium parvum inosine 5′ monophosphate dehydrogenase

Cryptosporidium parvum and related species are zoonotic intracellular parasites of the intestine. Cryptosporidium is a leading cause of diarrhea in small children around the world. Infection can cause severe pathology in children and immunocompromised patients. This waterborne parasite is resistant...

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Bibliografiska uppgifter
Huvudupphovsmän: Gorla, Suresh Kumar, Kavitha, Mandapati, Zhang, Minjia, Liu, Xiaoping, Sharling, Lisa, Gollapalli, Deviprasad R., Striepen, Boris, Hedstrom, Lizbeth, Cuny, Gregory D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635066/
https://ncbi.nlm.nih.gov/pubmed/22950983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm3007917
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