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Oxanosine monophosphate is a covalent inhibitor of inosine 5’-monophosphate dehydrogenase

Reactive nitrogen species (RNS) are produced during infection and inflammation and the effects of these agents on proteins, DNA and lipids are well recognized. In contrast, the effects of RNS damaged metabolites are less appreciated. 5–Amino–3–β–(D–ribofuranosyl)–3 H–imidazo–[4,5–d][1,3]oxazine–7–on...

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Detalhes bibliográficos
Publicado no:Chem Res Toxicol
Main Authors: Yu, Runhan, Kim, Youngchang, Maltseva, Natalia, Braunstein, Philip, Joachimiak, Andrzej, Hedstrom, Lizbeth
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467267/
https://ncbi.nlm.nih.gov/pubmed/30746940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00342
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