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Oxanosine monophosphate is a covalent inhibitor of inosine 5’-monophosphate dehydrogenase

Reactive nitrogen species (RNS) are produced during infection and inflammation and the effects of these agents on proteins, DNA and lipids are well recognized. In contrast, the effects of RNS damaged metabolites are less appreciated. 5–Amino–3–β–(D–ribofuranosyl)–3 H–imidazo–[4,5–d][1,3]oxazine–7–on...

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Bibliografiske detaljer
Udgivet i:Chem Res Toxicol
Main Authors: Yu, Runhan, Kim, Youngchang, Maltseva, Natalia, Braunstein, Philip, Joachimiak, Andrzej, Hedstrom, Lizbeth
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467267/
https://ncbi.nlm.nih.gov/pubmed/30746940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00342
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