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Oxanosine monophosphate is a covalent inhibitor of inosine 5’-monophosphate dehydrogenase

Reactive nitrogen species (RNS) are produced during infection and inflammation and the effects of these agents on proteins, DNA and lipids are well recognized. In contrast, the effects of RNS damaged metabolites are less appreciated. 5–Amino–3–β–(D–ribofuranosyl)–3 H–imidazo–[4,5–d][1,3]oxazine–7–on...

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Vydáno v:Chem Res Toxicol
Hlavní autoři: Yu, Runhan, Kim, Youngchang, Maltseva, Natalia, Braunstein, Philip, Joachimiak, Andrzej, Hedstrom, Lizbeth
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467267/
https://ncbi.nlm.nih.gov/pubmed/30746940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00342
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