Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA

Double homeobox (DUX) transcription factors are unique to eutherian mammals. DUX4 regulates expression of repetitive elements during early embryogenesis, but misexpression of DUX4 causes facioscapulohumeral muscular dystrophy (FSHD) and translocations overexpressing the DUX4 double homeodomain cause...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Lee, John K., Bosnakovski, Darko, Toso, Erik A., Dinh, Tracy, Banerjee, Surajit, Bohl, Thomas E., Shi, Ke, Orellana, Kayo, Kyba, Michael, Aihara, Hideki
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463520/
https://ncbi.nlm.nih.gov/pubmed/30540931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.11.060
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