Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA

Double homeobox (DUX) transcription factors are unique to eutherian mammals. DUX4 regulates expression of repetitive elements during early embryogenesis, but misexpression of DUX4 causes facioscapulohumeral muscular dystrophy (FSHD) and translocations overexpressing the DUX4 double homeodomain cause...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Lee, John K., Bosnakovski, Darko, Toso, Erik A., Dinh, Tracy, Banerjee, Surajit, Bohl, Thomas E., Shi, Ke, Orellana, Kayo, Kyba, Michael, Aihara, Hideki
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463520/
https://ncbi.nlm.nih.gov/pubmed/30540931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.11.060
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