Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA

Double homeobox (DUX) transcription factors are unique to eutherian mammals. DUX4 regulates expression of repetitive elements during early embryogenesis, but misexpression of DUX4 causes facioscapulohumeral muscular dystrophy (FSHD) and translocations overexpressing the DUX4 double homeodomain cause...

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Publicado en:Cell Rep
Autores principales: Lee, John K., Bosnakovski, Darko, Toso, Erik A., Dinh, Tracy, Banerjee, Surajit, Bohl, Thomas E., Shi, Ke, Orellana, Kayo, Kyba, Michael, Aihara, Hideki
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6463520/
https://ncbi.nlm.nih.gov/pubmed/30540931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.11.060
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