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Ultrasonication-based rapid amplification of α-synuclein aggregates in cerebrospinal fluid
α-Synuclein aggregates, a key hallmark of the pathogenesis of Parkinson’s disease, can be amplified by using their seeding activity, and the evaluation of the seeding activity of cerebrospinal fluid (CSF) is reportedly useful for diagnosis. However, conventional shaking-based assays are time-consumi...
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| 發表在: | Sci Rep |
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| Main Authors: | , , , , , , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6461702/ https://ncbi.nlm.nih.gov/pubmed/30979935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42399-0 |
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